PicPod 17 is a pro/con debate on the use of inhaled nitric oxide for paediatric ARDS. Harish argues that Nitric Oxide has no place in PICU, and Patrick argues that we should use it in targeted cases.
What are the pathophysiological mechanisms with ARDS? Is it the same for children and for adults? How might nitric oxide be beneficial theoretically?
What is the evidence base behind nitric oxide? Is there any high quality evidence in children? What studies are there, and what are their weaknesses and strengths?
Propensity matched studies: can we trust them? And, finally, why reading the online appendices on a paper is really important.
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